Narin Osman Selected Research

N- (4- methyl- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)phenyl)- N'- phenylurea

11/2008

Pyrido-pyrimidine derivative CYC10424 inhibits glycosaminoglycan changes on vascular smooth muscle-derived proteoglycans and reduces lipoprotein binding.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Narin Osman Research Topics

Disease

27	Atherosclerosis 01/2019 - 01/2005
7	Cardiovascular Diseases (Cardiovascular Disease) 02/2015 - 01/2005
3	Hyperglycemia 12/2010 - 05/2006
3	Hypertension (High Blood Pressure) 12/2008 - 05/2006
2	Atherosclerotic Plaque (Atheroma) 01/2016 - 05/2014
2	Macular Degeneration (Age-Related Maculopathy) 01/2016 - 01/2016
2	Vascular Diseases (Vascular Disease) 02/2015 - 12/2010
2	Insulin Resistance 03/2008 - 05/2006
1	Amyloidosis 01/2019
1	Wounds and Injuries (Trauma) 01/2018
1	Melanoma (Melanoma, Malignant) 07/2017
1	Streptococcal Infections (Streptococcal Infection) 01/2016
1	Myocardial Infarction 01/2016
1	Pathologic Processes 01/2016
1	Stroke (Strokes) 01/2016
1	Neointima 03/2013
1	Aortic Valve Disease 03/2013
1	Type 2 Diabetes Mellitus (MODY) 03/2008
1	Hypertriglyceridemia 01/2007
1	Inflammation (Inflammations) 01/2007
1	Hypercholesterolemia 01/2007
1	Dyslipidemias (Dyslipidemia) 05/2006

Drug/Important Bio-Agent (IBA)

24	Proteoglycans (Proteoglycan)IBA 01/2019 - 01/2005
14	LipidsIBA 01/2016 - 01/2007
10	GlycosaminoglycansIBA 01/2019 - 01/2005
7	Lipoproteins (Lipoprotein)IBA 01/2019 - 01/2005
7	LDL Lipoproteins (beta Lipoproteins)IBA 01/2018 - 03/2008
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 05/2006
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019 - 12/2010
4	BiglycanIBA 01/2018 - 10/2008
4	Platelet-Derived Growth FactorIBA 05/2014 - 11/2008
3	Thrombin FDA Link 01/2019 - 03/2013
3	Phosphotransferases (Kinase)IBA 01/2018 - 08/2008
2	Messenger RNA (mRNA)IBA 01/2018 - 01/2016
2	tyrosine receptor (receptor, tyrosine)IBA 07/2017 - 08/2008
2	ApolipoproteinsIBA 01/2016 - 05/2014
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 05/2014 - 04/2013
2	Endothelin-1 (Endothelin 1)IBA 08/2008 - 07/2008
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 08/2008 - 07/2008
2	Peptides (Polypeptides)IBA 08/2008 - 07/2008
2	oxidized low density lipoproteinIBA 03/2008 - 01/2007
1	Plasminogen Activator Inhibitor 1IBA 01/2018
1	galactosaminoglycanIBA 01/2018
1	TOR Serine-Threonine KinasesIBA 07/2017
1	VemurafenibIBA 07/2017
1	Fusidic Acid (Fucithalmic)IBA 01/2016
1	EnzymesIBA 01/2016
1	Anti-Infective Agents (Microbicides)IBA 01/2016
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 02/2015
1	IsomerasesIBA 02/2015
1	Pharmaceutical PreparationsIBA 04/2014
1	gingerolIBA 07/2013
1	S 6 (S-6)IBA 07/2013
1	Endothelins (Endothelin)IBA 04/2013
1	Tyrosine (L-Tyrosine)FDA Link 04/2013
1	A-factor (Streptomyces)IBA 12/2010
1	Threonine (L-Threonine)FDA Link 08/2010
1	Serine (L-Serine)FDA Link 08/2010
1	Growth Factor ReceptorsIBA 08/2010
1	low density lipoprotein inhibitorIBA 06/2010
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2010
1	DecorinIBA 01/2010
1	ChondroitinIBA 08/2009
1	Dermatan SulfateIBA 08/2009
1	p38 Mitogen-Activated Protein KinasesIBA 12/2008
1	N- (4- methyl- 3- ((4- pyridin- 3- ylpyrimidin- 2- yl)amino)phenyl)- N'- phenylureaIBA 11/2008
1	dermatan sulfate proteoglycanIBA 10/2008
1	rho-Associated KinasesIBA 08/2008
1	beta-ArrestinsIBA 08/2008
1	Mitogen-Activated Protein KinasesIBA 08/2008
1	Type C PhospholipasesIBA 08/2008
1	Adenylyl Cyclases (Adenylyl Cyclase)IBA 08/2008
1	Complement System Proteins (Complement)IBA 07/2008
1	Amino Acids FDA Link 07/2008
1	Hormones (Hormone)IBA 07/2008
1	2,4-thiazolidinedione (thiazolidinedione)IBA 03/2008
1	Advanced Glycation End ProductsIBA 01/2007
1	Glucose (Dextrose)FDA LinkGeneric 05/2006
1	Insulin ReceptorIBA 05/2006
1	Insulin (Novolin)FDA Link 05/2006
1	AndrogensIBA 07/2005
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2005
1	Antihypertensive Agents (Antihypertensives)IBA 01/2005

Therapy/Procedure

4	Therapeutics 12/2008 - 01/2005
1	RNAi Therapeutics 01/2019